Polynucleotide Treatments
Next Level Regenerative Skin Medicine in Hampshire
If you are looking for a treatment that improves skin quality from within rather than simply masking the signs of ageing, polynucleotide therapy offers an exciting new approach to facial rejuvenation.
At CJA Aesthetics Clinics in Portsmouth, Southampton and Winchester, we provide advanced doctor-led polynucleotide treatments designed to stimulate your skin's own repair mechanisms, restore hydration and improve overall skin health.
Unlike traditional fillers, which add volume, polynucleotides work at a cellular level to encourage collagen production, tissue regeneration and improved skin function. The result is healthier, stronger and more radiant skin that continues to improve over time.
Book a consultation with our medical team in Hampshire by calling 023 8033 2429 to find out what a difference it could make to your appearance. You can also book a convenient online video consultation or face to face consultation.
Key Takeaways
- Polynucleotide injections stimulate natural collagen production for firmer, smoother, healthier-looking skin.
- It regenerates skin at a cellular level rather than simply adding temporary volume.
- Improves hydration, elasticity and skin texture for a fresher, more radiant complexion.
- Helps calm inflammation and redness, making it suitable for rosacea and acne-prone skin.
- Polynucleotide boosters are effective for the face, neck, décolletage, scars and even hair restoration.
- Minimal downtime with gradual, natural-looking results that continue improving over several weeks.
- Doctor-led treatment at our Hampshire clinic using premium licensed polynucleotide products.
What Are Polynucleotides?
Polynucleotides (PN) are naturally occurring chains of nucleotides that form part of the structure of DNA and RNA in all living cells. In aesthetic medicine, highly purified polynucleotides are used for their remarkable regenerative and bio-stimulating properties.
When carefully injected into the skin, they help to:
- Stimulate fibroblast activity
- Increase collagen and elastin production
- Improve microcirculation
- Enhance tissue repair and regeneration
- Reduce oxidative stress and inflammation
- Restore deep hydration within the skin
Fibroblasts are the cells responsible for producing collagen, elastin and connective tissue, all of which are essential for maintaining firm, smooth and youthful-looking skin. As we age, fibroblast activity slows down, leading to thinner, drier and less elastic skin. Polynucleotide therapy helps to reactivate these natural repair processes.
How Do Polynucleotide Treatments Work?
Polynucleotides act as biological messengers within the skin. After injection, they create an environment that supports cellular repair and regeneration rather than simply filling or stretching the skin.
The treatment works in several ways:
Collagen Stimulation: Polynucleotides encourage fibroblasts to produce new collagen fibres, improving skin firmness and elasticity over the following weeks and months.
Tissue Repair: They help repair damaged or stressed skin cells, making them particularly useful for sun-damaged, ageing or sensitised skin.
Deep Hydration: PN molecules attract and retain water within the skin, leading to improved hydration, softness and radiance without creating excessive volume.
Anti-Inflammatory Action: Their antioxidant and anti-inflammatory effects can help calm redness, irritation and inflammatory skin conditions such as rosacea and acne.
This makes polynucleotide therapy a true skin quality treatment, focusing on regeneration, resilience and long-term skin health.
What To Expect During Treatment
Your treatment begins with a comprehensive consultation with one of our fully qualified doctors. You will receive personalised advice on how to prepare for treatment and what results you can realistically expect. We will assess:
- Your skin concerns and treatment goals
- Skin quality, hydration and elasticity
- Medical history and current medications
- Any previous aesthetic treatments
- Suitability for polynucleotide therapy
Common treatment areas include under-eye area, full face, neck and décolletage, hands, and scalp for hair regeneration.
During the procedure, the treatment area is thoroughly cleansed, and a topical anaesthetic cream may be applied if required. Polynucleotides are then placed into the skin using a series of tiny superficial injections.
The procedure usually takes 30-45 minutes, depending on the size and number of areas being treated and most clients describe the injections as mildly uncomfortable rather than painful. After your appointment, you may notice:
- Small raised bumps at the injection sites
- Mild redness
- Slight swelling or tenderness
- Occasional minor bruising
These effects are temporary and usually settle within 24-72 hours. Most clients are able to return to normal daily activities immediately.
What Conditions Can Polynucleotides Treat?
This versatile treatment has a wide range of applications across the face, body and scalp.
Facial Rejuvenation: It is excellent for improving skin quality around the eyes, cheeks, mouth, neck and decolletage.
Rosacea: Polynucleotides may help reduce redness, inflammation and skin sensitivity, supporting a calmer and more resilient skin barrier.
Acne & Acne Scarring: By promoting tissue repair and reducing inflammation, they can improve both active acne-prone skin and the appearance of post-acne scarring.
Sun-Damaged Skin: It is particularly effective for skin affected by UV damage. For example, you might want to treat fine lines caused by sun exposure, loss of skin elasticity, uneven pigmentation.
Scars & Stretch Marks: The collagen-stimulating effects may help soften and improve the appearance of surgical scars, acne scars, stretch marks.
Hair Regeneration: Polynucleotides are increasingly used as part of hair restoration programmes for patients experiencing thinning hair, early androgenetic alopecia, post-partum hair shedding, and general scalp health concerns.
FAQs About Polynucleotide Injections
Are Polynucleotide treatments safe?
«Polynucleotides are naturally occurring molecules that play a role in cellular repair and regeneration. The treatments offered at CJA are produced by Italian pharmaceutical company Mastelli and are based on the very latest developments in skin care science.
The treatments use filtered, ultra-purified and sterilised DNA fragments and are the result of decades of scientific research and medical developments. Rigorous testing has revealed no adverse or allergic reactions. Polynucleotide skin boosters are the gold standard in skin regeneration treatments.
Are there any side effects to polynucleotide injections?
«You may experience some slight bruising and swelling (as with any injectable treatment) but this will usually dissipate within a few hours.
Where does the DNA used in polynucleotide treatments come from?
«The DNA used comes from salmon (who are not harmed in the process). Human DNA is surprisingly similar to salmon DNA, which allows scientists to use small fractions of it to produce these highly effective treatments. Rest assured that the DNA fractions are subject to a highly specialised filtration, sterilisation and purification process before they are used in the production serums. Comprehensive clinical trials have revealed no adverse or allergic reactions to the treatment, including amongst fish allergy sufferers.
How soon will I see results from a polynucleotide treatment?
«You should start to see improvements in your skin texture about a week to 10 days after treatment. The full results will be visible in around 3-4 weeks.
At this point we recommend a follow-up treatment. For best results in the long term we recommend a course of at least 3 treatments, approximately 3 weeks apart.
What's NEWEST Polynucleotides Treatment?
«NEWEST Polynucleotides-HPT TM harnesses the power of DNA fragments to regenerate your skin from within, combined with the hydrating power of hyaluronic acid. It's is a specially-formulated gel that is injected into your face, neck, and décolletage to restore radiance and freshness in mature and dehydrated skin.
NEWEST is especially suitable for mature skin. We offer a wide range of polynucleotide treatments to address a variety of skin concerns.
What goes into a polynucleotide injection?
«Polynucleotides are DNA fragments derived from natural sources, carefully formulated to stimulate collagen production, boost cellular repair, and promote skin regeneration. These powerful molecules penetrate deep into your skin, jump-starting the rejuvenation process and restoring your complexion's vitality from within.
What after care will I need?
«We will give you full details of aftercare requirements and what to expect at your initial consultation. There is no downtime following treatment, but you will need to avoid touching or washing your face for up to 4 hours and avoid make up for 12 hours.
Are there any risks to polynucleotide injections?
«Polynucleotide injections are generally considered very safe when performed by a qualified medical professional using licensed products. Because polynucleotides are biocompatible molecules that closely resemble substances naturally found in the body, the risk of serious adverse reactions is low.
As with any injectable treatment, some temporary side effects can occur, including:
Mild redness at the injection sites
Slight swelling or tenderness
Small raised bumps immediately after treatment
Minor bruising
Temporary sensitivity in the treated area
These effects usually settle within 24-72 hours. Serious complications such as infection or allergic reaction are rare, particularly when treatment is carried out in a CQC registered medical clinic with appropriate sterile techniques.
At CJA Aesthetics Southampton, every patient undergoes a full medical consultation before treatment to ensure polynucleotide injections are suitable for them and to minimise any potential risks. We also provide detailed aftercare advice to support a smooth recovery and the best possible results.